The short answer is yes.
According to criminaldefenselawyer.com, even though 18 states in the U.S. have legalized medical marijuana, none so far have declared that it is OK to drive while under the influence of medical weed. You will still get a DUI if you medicate and then drive.
However, Colorado Marijuana and Driving Frequently Asked Questions points out that you can’t be targeted as a DUI candidate just because you have your card. Having a med card on you is not probable cause, at least not in the Rocky Mountain state. Be sure to review your state’s laws on probable cause as well.